PLA2G7 wt Allele

Preferred Label : PLA2G7 wt Allele;

NCIt synonyms : Platelet-Activating Factor Acetylhydrolase, Plasma Gene; LP-PLA2; Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma) wt Allele; PAFAD; PAFAH; LDL-PLA2;

NCIt definition : Human PLA2G7 wild-type allele is located within 6p21.2-p12 and is approximately 31 kb in length. This allele, which encodes platelet-activating factor acetylhydrolase protein, plays a role in the modulation of the inflammatory activity of platelet-activating factor. Mutation of the gene is associated with platelet-activating factor acetylhydrolase deficiency and increased susceptibility to asthma or atopy.;

GenBank Accession Number : U20157;

Details

Origin ID

C122065;

UMLS CUI

C4050220;

Automatic exact mappings (from CISMeF team)
- 1-alkyl-2-acetylglycerophosphocholine esterase [MeSH Descriptor]
- 1-alkyl-2-acetylglycerophosphocholine esterase activity [GO term]
- Lipoprotein associated phospholipase A2 [LOINC component]
- Phospholipase a2, group VII [OMIM gene]
- Platelet-activating factor acetylhydrolase deficiency [OMIM Phenotype]
- platelet activating factor acetylhydrolase 1b regulatory subunit 1 [ORDO Gene]
OMIM relation
- Phospholipase a2, group VII [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Ether Lipid Metabolism Pathway [NCIt concept]
- Lissencephaly-1 Gene in Neuronal Migration and Development [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Lipid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients