Integrin Alpha4/Beta7

Preferred Label : Integrin Alpha4/Beta7;

NCIt synonyms : LPAM; Alpha 4 Beta 7; Integrin Alpha-4/Beta-7; Alpha4 Beta7 Integrin; Alpha4/Beta7; Alpha4-Beta7; Alpha 4 Beta 7 Integrin; LPAM-1; alpha4beta7 Integrin; Alpha4-Beta7 Integrin; Integrin Alpha4 Beta7; Alpha4/Beta7 Integrin; Alpha(4)Beta(7) Integrin; Integrin a4b7; Lymphocyte Peyer Patch Adhesion Molecule; Integrin Alpha4-Beta7;

NCIt definition : Integrin alpha4/beta7 is a protein complex comprised of a heterodimer of integrin alpha4 and integrin beta7. This complex plays a role in cell-cell adhesion, cell-matrix adhesion, lymphocyte homing and host defense mechanisms.;

Details

Origin ID

C121993;

UMLS CUI

C0648695;

Automatic exact mappings (from CISMeF team)
- integrin alpha4beta7 [MeSH concept]
- integrin alpha4beta7 [MeSH Supplementary Concept]
- melphalan [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- integrin alpha4beta7 [MeSH Supplementary Concept]
- integrin alpha4beta7 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Ligand Binding [NCIt concept]
has_gene_product_element
- Integrin Alpha-4 [NCIt concept]
is_target
- Vedolizumab [NCIt concept]
related_to_genetic_biomarker
- ITGA4 Gene [NCIt concept]
- ITGB7 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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