Giant Cell Tumor of Bone

Preferred Label : Giant Cell Tumor of Bone;

NCIt synonyms : Osteoclastoma; Giant Cell Tumor of the Bone; GCTB;

NCIt related terms : Giant cell tumor of bone, NOS; GIANT CELL TUMOR, BENIGN; Osteoclastoma, Benign; Benign Bone Giant Cell Tumor;

NCIt definition : A benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint.;

Alternative definition : CDISC: A benign neoplasm of bone comprised of giant cells (osteoclast-like) and mononuclear cells.;

Neoplastic status : Undetermined;

Details

Origin ID

C121932;

UMLS CUI

C0206638;

Automatic exact mappings (from CISMeF team)
- Giant cell tumor of bone NOS [ICD-9 code]
- Giant cell tumor of bone, NOS [ICD-O code]
- benign giant cell tumor [DO Concept]
Currated CISMeF NLP mapping
- Benign bone giant cell tumor [MedDRA LLT]
- Benign bone giant cell tumour [MedDRA LLT]
- Bone giant cell tumor [MedDRA LLT]
- Bone giant cell tumor benign [MedDRA LLT]
- Bone giant cell tumour [MedDRA Preferred Term]
- Bone giant cell tumour benign [MedDRA Preferred Term]
- Giant cell tumor of bone [HPO term]
- Giant cell tumor of bone [ORDO Disease]
- Giant cell tumor of bone (disorder) [SNOMED CT concept]
- Giant cell tumor of bone (morphologic abnormality) [SNOMED CT concept]
- bone giant cell tumor [DO Concept]
- giant cell neoplasm of bone [Disease (Nov.)]
- giant cell tumor of bone [MeSH Descriptor]
- giant cell tumor of bone [MeSH concept]
- giant cell tumor of bone, nos [SNOMED Notion]
DO Cross reference
- bone giant cell tumor [DO Concept]
Disease excludes abnormal cell
- Malignant Mesenchymal Spindle Cell [NCIt concept]
- Malignant Ovoid to Spindle-Shaped Fibrohistiocytic Cell [NCIt concept]
Excludes anatomical site(s)
- Lymphatic System [NCIt concept]
Has associated anatomic sites
- Bone [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Musculoskeletal System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Benign bone giant cell tumor [MedDRA LLT]
- Benign bone giant cell tumour [MedDRA LLT]
- Bone giant cell tumor [MedDRA LLT]
- Bone giant cell tumor benign [MedDRA LLT]
- Bone giant cell tumour [MedDRA Preferred Term]
- Bone giant cell tumour benign [MedDRA Preferred Term]
- Giant cell tumor of bone [ORDO Disease]
- Giant cell tumor of bone [HPO term]
- Giant cell tumor of bone (disorder) [SNOMED CT concept]
- Giant cell tumor of bone (morphologic abnormality) [SNOMED CT concept]
- Osteoclastoma [MedDRA LLT]
- bone giant cell tumor [DO Concept]
- giant cell neoplasm of bone [Disease (Nov.)]
- giant cell tumor of bone [MeSH Descriptor]
- giant cell tumor of bone [MeSH concept]
- giant cell tumor of bone, nos [SNOMED Notion]
concept_is_in_subset
- CDISC SEND Terminology [NCIt concept]
- CDISC SEND Tumor Findings Results Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_has_abnormal_cell
- Giant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Mononuclear Stromal Cell [NCIt concept]
- Osteoclast-Like Giant Cell [NCIt concept]
disease_has_finding
- Locally Aggressive Lesion [NCIt concept]
- Lytic Bone Lesion [NCIt concept]
- Pain [NCIt concept]
- Swelling [NCIt concept]
disease_has_normal_cell_origin
- Cell [NCIt concept]
disease_has_normal_tissue_origin
- Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone [NCIt concept]
disease_mapped_to_gene
- H3-3A Gene [NCIt concept]
disease_may_have_molecular_abnormality
- H3-3A Gene Mutation [NCIt concept]
pathogenesis_of_disease_involves_gene
- H3-3A Gene [NCIt concept]
- H3-3A wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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