H3-3A wt Allele

Preferred Label : H3-3A wt Allele;

NCIt synonyms : RP11-396C23.1; H3F3; LOC347376; H3.3A; MGC87783; MGC87782; PP781; H3 Histone Family Member 3A Gene; H3.3 Histone A wt Allele; H3F3A;

NCIt related terms : H3F3A wt Allele;

NCIt definition : Human H3-3A wild-type allele is located in the vicinity of 1q42.12 and is approximately 10 kb in length. This allele, which encodes histone H3.3 protein, plays a role in both nucleosome assembly and transcriptional regulation.;

NCIt note : Somatic mutation of the H3F3A gene may be associated with diffuse intrinsic pontine glioma. (Nature Genetics. 2012; 44:251-253.);

GenBank Accession Number : BC029405;

Details

Origin ID

C101444;

UMLS CUI

C3540522;

OMIM relation
- H3 histone, family 3a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Giant Cell Tumor of Bone [NCIt concept]
gene_is_element_in_pathway
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]
- Chromatin Structural Process [NCIt concept]
- Coagulation Process [NCIt concept]
- Gene Regulation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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