" /> Anti-CEA-CAR Autologous T Lymphocytes - CISMeF





Preferred Label : Anti-CEA-CAR Autologous T Lymphocytes;

NCIt synonyms : Autologous Anti-CEA CAR-T Cells;

NCIt definition : Autologous lymphocytes transduced with a retroviral vector encoding a chimeric antigen receptor (CAR) specific for the tumor-associated antigen human carcinoembryonic antigen (CEA), with potential immunostimulating and antineoplastic activities. Upon administration, the anti-CEA-CAR autologous T-lymphocytes target and bind to tumor cells expressing CEA, which results in the cytotoxic T-lymphocyte (CTL)-mediated cell killing of CEA-expressing tumor cells. CEA is overexpressed in various tumor cell types.;

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31/07/2025


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