Preferred Label : P-cadherin Inhibitor PCA062;
NCIt synonyms : P-cadherin Antagonist PCA062; P-CAD Inhibitor PCA062;
NCIt definition : An agent that inhibits p-cadherin, with potential antineoplastic activity. Upon intravenous
infusion, PCA062 binds to and inhibits the activity of p-cadherin. Inhibition of the
activity of p-cadherin may inhibit both invasion and proliferation of p-cadherin expressing
tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family,
is overexpressed in a variety of tumors and plays a role in cell adhesion, motility,
invasion, and proliferation.;
Molecule name : PCA062;
Origin ID : C121216;
UMLS CUI : C4053579;
Semantic type(s)
- concept_is_in_subset
- has_target
