Pentetate Calcium

Preferred Label : Pentetate Calcium;

NCIt synonyms : Ca-DTPA; Calcium DTPA; Diethylenetriaminepentaacetic Acid, Calcium Salt; Calcium N,N-bis(2-(bis(carboxymethyl)amino)ethyl)glycinate (1:1);

NCIt related terms : pentetic acid calcium;

NCIt definition : The calcium salt form of diethylene triamine pentaacetate (Ca-DTPA or pentetate calcium), with chelating activity. Upon administration, Ca-DTPA loses the Ca ion to form stable chelates with metal ions because DTPA has a higher affinity for heavy metal ions than for Ca ions. Specifically, this agent is able to bind to and form strong complexes with radioactive plutonium, americium, and cerium after internal contamination. The formation of these heavy metal chelates enhances radionuclide excretion. enhances radionuclide excretion.;

Alternative definition : NCI-GLOSS: A drug that protects healthy tissues from the toxic effects of anticancer drugs.;

UNII : W0655Y0HSJ;

CAS number : 2531-75-1;

Codes from synonyms : CDR0000045514;

Details

Origin ID

C120569;

UMLS CUI

C3535910;

Automatic exact mappings (from CISMeF team)
- Ca-DTPA [MeSH concept]
- pentetic acid [MeSH Descriptor]
See also inter- (CISMeF)
- pentetate calcium trisodium [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Pentetic Acid [NCIt concept]
is_salt_form_of
- Pentetic Acid [NCIt concept]

Keyword's position in hierarchy(ies) :

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