" /> Lifileucel - CISMeF





Preferred Label : Lifileucel;

NCIt synonyms : Autologous TIL LN-144; Autologous Tumor Infiltrating Lymphocytes LN-144;

NCIt related terms : Lifileuecel;

NCIt definition : A preparation of autologous tumor infiltrating lymphocytes (TILs), with potential antineoplastic activity. TILs are isolated from a patient's tumor tissue, cultured in vitro with high-dose interleukin-2 (lL-2), further selected based on antigen specificity and tumor reactivity, and the selected TILs are subsequently expanded. Upon re-introduction of lifileucel into the patient, the TILs re-infiltrate the tumor, specifically recognize the tumor-associated antigens (TAAs), and initiate tumor cell lysis. IL-2 induces the proliferation and expansion of TILs in vitro.;

UNII : R0835E18NH;

CAS number : 2306267-74-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2306267-74-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Contego;

Molecule name : LN-144;

Codes from synonyms : 114432;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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