Histone H3 Acetyl Lys28

Preferred Label : Histone H3 Acetyl Lys28;

NCIt synonyms : Histone H3 Acetyl Lys27; H3K28ac; Histone H3 Acetyl Lysine 28;

NCIt related terms : H3K27ac;

NCIt definition : A post-translationally modified form of histone H3 where the lysine residue at position 28 is acetylated. This modification may be a marker for transcriptional enhancement.;

NCIt note : Even though the literature refers to lysine 27 acetylation/methylation or amino acid variation/mutation, RefSeq indicates that the lysine is located at amino acid position 28 in histone H3. (see https://link.springer.com/article/10.1007/s00401-018-1867-2);

Details

Origin ID

C120023;

UMLS CUI

C3898882;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
related_to_genetic_biomarker
- Histone H3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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