2-Hydroxybutyrate

Preferred Label : 2-Hydroxybutyrate;

NCIt synonyms : Alpha-Hydroxybutanoate; 2-OH-Butyrate; Alpha-Hydroxybutyrate; 2-Hydroxybutanoate; 2-OH Butyrate; a-HB;

NCIt definition : A hydroxy fatty acid anion and conjugate base of 2-hydroxybutyric acid. 2-Hydroxybutyrate is a metabolite produced by the conversion of cystathionine to cysteine in the glutathione biosynthesis pathway. The amount of 2-hydroxybutyrate secreted in the urine can reflect changes in the rate of glutathione synthesis, which is altered by oxidative stress or toxin exposure.;

ChEBI ID : CHEBI:64552;

Details

Origin ID

C120002;

UMLS CUI

C1291204;

Automatic exact mappings (from CISMeF team)
- 2-amino-4-hydroxybenzenesulfonic acid [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- 2-hydroxybutyrate (substance) [SNOMED CT concept]
- Alpha hydroxybutyrate [LOINC component]
- alpha-hydroxybutyrate [MeSH concept]
False automatic mappings
- Hemoglobin [LOINC component]
- Hemoglobin (substance) [SNOMED CT concept]
- Hemoglobin S [LOINC component]
- Hemoglobin S (substance) [SNOMED CT concept]
- hemoglobin AS [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- 2-hydroxybutyrate (substance) [SNOMED CT concept]
- Alpha hydroxybutyrate [LOINC component]
Validated automatic mappings to BTNT
- 2-hydroxybutyric acid [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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