Exhausted T-Cell

Preferred Label : Exhausted T-Cell;

NCIt synonyms : Exhausted T-Lymphocyte; Exhausted T Lymphocyte; Exhausted T Cell;

NCIt definition : An effector T-lymphocyte that is losing or has lost the ability to kill virally infected cells. T-cell exhaustion occurs during infections with high viral loads and/or prolonged duration. These T-lymphocytes undergo a gradual phenotype change and in the final stage they are unable to mount a T-cell antiviral response and are highly susceptible to apoptosis.;

Details

Origin ID

C120000;

UMLS CUI

C3899239;

Anatomic structure is physical part of
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
Currated CISMeF NLP mapping
- T-Cell Exhaustion [MeSH Descriptor]
Semantic type(s)
- Cell [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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