Preferred Label : Gallium Ga 68 Gozetotide;
NCIt synonyms : Gallium-68 PSMA Ligand Glu-urea-Lys(Ahx)-HBED-CC; [68Ga]GaPSMA-11; (68)Ga-labeled Glu-urea-Lys(Ahx)-HBED-CC; (68)Ga-PSMA Ligand Glu-urea-Lys(Ahx)-HBED-CC; 68Ga-PSMA-11; Gallium Ga 68 PSMA-11; PSMA-HBED-CC GA-68; (68)Ga labeled Glu-NH-CO-NH-Lys(Ahx)-HBED-CC; Ga-68 labeled PSMA-11; [68Ga] Prostate-specific Membrane Antigen 11; 68Ga-HBED-CC-PSMA; (68)Gallium-PSMA Ligand Glu-urea-Lys(Ahx)-HBED-CC; 68Ga-labeled Glu-NH-CO-NH-Lys(Ahx)-HBED-CC; 68Ga-PSMA; 68Ga-DKFZ-PSMA-11; Ga-68 labeled DKFZ-PSMA-11; Gallium-68 PSMA; (68Ga)Glu-urea-Lys(Ahx)-HBED-CC; GaPSMA; 68Ga-PSMA-HBED-CC; Ga PSMA; GA-68 PSMA-11; Gallium Ga 68-labeled PSMA-11;
NCIt related terms : GALLIUM GA-68 GOZETOTIDE;
NCIt definition : A radioconjugate composed of a human prostate specific membrane antigen (PSMA)-targeting
ligand, Glu-urea-Lys(Ahx) (Glu-NH-CO-NH-Lys(Ahx)), conjugated, via the acyclic radiometal
chelator N,N'-bis [2-hydroxy-5-(carboxyethyl)benzyl] ethylenediamine-N,N'-diacetic
acid (HBED-CC), to the radioisotope gallium Ga 68, with potential use as a tracer
for PSMA-expressing tumors during positron emission tomography (PET). Upon intravenous
administration of the gallium Ga 68 gozetotide, the Glu-urea-Lys(Ahx) moiety targets
and binds to PSMA-expressing tumor cells. Upon internalization, PSMA-expressing tumor
cells can be detected during PET imaging. PSMA, a tumor-associated antigen and type
II transmembrane protein, is expressed on the membrane of prostatic epithelial cells
and overexpressed on prostate tumor cells.;
UNII : ZJ0EKR6M10;
InChIKey : AEBYHKKMCWUMKX-LNTZDJBBSA-K;
CAS number : 1906894-20-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1906894-20-9
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G-SRS /a ;
Molecule name : AAA 517; AAA-517;
Origin ID : C118961;
UMLS CUI : C3656970;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_target
