N-Methyl-D-Aspartate Receptor

Preferred Label : N-Methyl-D-Aspartate Receptor;

NCIt synonyms : NMDA Receptor; NMDAR;

NCIt definition : A protein complex that plays a role in both NMDA binding and ion transport. It is a heterotetramer consisting of 2 glutamate [NMDA] receptor subunit zeta-1 proteins and 2 epsilon subunits (glutamate [NMDA] receptor subunit epsilon-1, -2, -3 or -4).;

Alternative definition : CDISC: An antigen of the NMDA receptor that binds to and mediates the neurotransmission of N-methyl-D-aspartic acid and iron. It can be considered as an autoantigen and is commonly associated with autoimmune encephalitis.;

Details

Origin ID

C118457;

UMLS CUI

C0080093;

Automatic exact mappings (from CISMeF team)
- NMDA glutamate receptor activity [GO term]
- NMDAR [LOINC component]
- receptors, N-Methyl-D-Aspartate [MeSH concept]
- receptors, n-methyl-d-aspartate [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NMDAR [LOINC component]
- receptors, N-Methyl-D-Aspartate [MeSH concept]
- receptors, n-methyl-d-aspartate [MeSH Descriptor]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
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- Receptor [NCIt concept]
gene_product_plays_role_in_biological_process
- Receptor Signaling [NCIt concept]
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- Glutamate Receptor Ionotropic, NMDA 2A [NCIt concept]
- Glutamate Receptor Ionotropic, NMDA 2B [NCIt concept]
- Glutamate Receptor Ionotropic, NMDA 2D [NCIt concept]

Keyword's position in hierarchy(ies) :

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