receptors, n-methyl-d-aspartate

Preferred Label : receptors, n-methyl-d-aspartate;

MeSH definition : A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.;

MeSH synonym : receptors, n methylaspartate; receptors, n-methylaspartate; nmda receptor-ionophore complex; n-methyl-d-aspartate receptors; n methyl d aspartate receptors; nmda receptors; receptors, nmda; nmda receptor ionophore complex; n-methylaspartate receptors; n methylaspartate receptors; receptors, N methyl D aspartate; NMDA Receptor; Receptor, NMDA; N-Methyl-D-Aspartate Receptor; N Methyl D Aspartate Receptor; Receptor, N-Methyl-D-Aspartate;

Is substance : O;

Details

Origin ID

D016194;

UMLS CUI

C0080093;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- N-Methyl-D-Aspartate Receptor [NCIt concept]
- NMDA glutamate receptor activity [GO term]
- NMDAR [LOINC component]
Indexing information
- (4-benzylpiperidin-1-yl)-(5(6)-hydroxy-1H-benzimidazol-2-yl)methanone [MeSH Supplementary Concept]
- (4-benzylpiperidin-1-yl)-(6-hydroxy-1H-indol-2-yl)methanone [MeSH Supplementary Concept]
- 1,3,3,5-tetramethyl-6-azabicyclo(3.2.1)octane [MeSH Supplementary Concept]
- 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido(3,4-f)quinoxaline-2,3-dione [MeSH Supplementary Concept]
- 1,5-(diethylamino)piperidine [MeSH Supplementary Concept]
- 1-(4'-aminophenyl)-3,5-dihydro-7,8-dimethoxy-4H-2m3-benzodiazepine-4-thione [MeSH Supplementary Concept]
- 1-(9-iodophenanthrene-3-carbonyl)piperazine-2,3-dicarboxylic acid [MeSH Supplementary Concept]
- 1-amino-3-fluoromethyl-5-methyladamantane [MeSH Supplementary Concept]
- 1-aminocyclopropane-1-carboxylic acid [MeSH Supplementary Concept]
- 1-ethenyl-3,3,5,5-tetramethylcyclohexylamine [MeSH Supplementary Concept]
- 1-phenyl-2-(1-amino-2-propynyl)-N,N-diethylcyclopropanecarboxamide [MeSH Supplementary Concept]
- 1-thioxo-1,2-dihydro(1,2,4)triazolo(4,3-a)quinoxalin-4(5H)-one [MeSH Supplementary Concept]
- 2,3-dihydro-6,7-dichloropyrido(2,3-b)pyrazine-8-oxide [MeSH Supplementary Concept]
- 2-(1,4-benzodioxan-6-yl)-4,5-dihydroimidazole [MeSH Supplementary Concept]
- 2-(1-phenylcyclohex-1-yl)ethanamine [MeSH Supplementary Concept]
- 2-amino-3-(5-chloro-1-phosphonomethyl-1H-benzoimidazol-2-yl)propionic acid [MeSH Supplementary Concept]
- 2-styryl-2-imidazoline [MeSH Supplementary Concept]
- 3,3-bis(3-fluorophenyl)propylamine [MeSH Supplementary Concept]
- 3,3-diphenylpropyl-N-glycinamide [MeSH Supplementary Concept]
- 3-(1-hydroxy-2-phosphonoethyl)-2-piperidinecarboxylic acid [MeSH Supplementary Concept]
- 3-(2-(3-aminophenyl)-2-carboxyvinyl)-4,6-dichloro-1H-indole-2-carboxylic acid [MeSH Supplementary Concept]
- 3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-1,7-diol [MeSH Supplementary Concept]
- 3-(aminomethyl)piperazine-2,5-dione [MeSH Supplementary Concept]
- 3-azido-5-methyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine [MeSH Supplementary Concept]
- 3-hydroxy-6,8-dimethyl-1H-1-benzazepine-2,5-dione [MeSH Supplementary Concept]
- 3-hydroxyimidazolidin-4-one [MeSH Supplementary Concept]
- 3a,5,6,6a-tetrahydro-4H--pyrrolo(3,4-d)isoxazole-3,6-dicarboxylic acid [MeSH Supplementary Concept]
- 4,5,9,10-Tetrahydro-1,4-ethanobenz(b)quinolizine [MeSH Supplementary Concept]
- 4,6-dichloro-3-((1-N-arylaminocarbonyl)-hydrazono)-1,3-dihydro-indole-2-one [MeSH Supplementary Concept]
- 4-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)phenol [MeSH Supplementary Concept]
- 4-(5-(4-bromophenyl)-3-(6-methyl-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-oxobutanoic acid [MeSH Supplementary Concept]
- 4-aminophenyl-1,2-dihydro-1-methyl-2-propylcarbamoyl-6,7-methylenedioxyphthalazine [MeSH Supplementary Concept]
- 4-benzyl-1-(4-(1H-imidazol-4-yl)but-3-ynyl)piperidine [MeSH Supplementary Concept]
- 4-benzyl-1-(4-(4-hydroxyphenyl)but-3-ynyl)piperidine [MeSH Supplementary Concept]
- 4-methylbenzyl 3-fluoro-4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate [MeSH Supplementary Concept]
- 4-methylbenzyl 4-((pyrimidin-2-ylamino)methyl)piperidine-1-carboxylate [MeSH Supplementary Concept]
- 4-trifluoromethoxy-N-(2-trifluoromethylbenzyl)benzamidine [MeSH Supplementary Concept]
- 5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1,3-dihydrobenzimidazol-2-one [MeSH Supplementary Concept]
- 5-(aminomethyl)piperazine-2,3-dione [MeSH Supplementary Concept]
- 5-amino-4,5,6,6a-tetrahydro-3aH-cyclopenta(d)isoxazole-3,5-dicarboxylic acid [MeSH Supplementary Concept]
- 7,8-dichloro-6-nitro-1H-1,5-benzodiazepine-2,4-(3H,5H)-dione [MeSH Supplementary Concept]
- 7-iodo-N-(1-phosphonoethyl)-5-aminomethylquinoxaline-2,3-dione [MeSH Supplementary Concept]
- 8,8,10,10-tetramethyl-1-azaspiro(5.5)undecane [MeSH Supplementary Concept]
- 8-chloro-1,4-dioxo-1,2,3,4-tetrahydropyridazino(4,5-b)quinoline [MeSH Supplementary Concept]
- 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine [MeSH Supplementary Concept]
- AZD6765 [MeSH Supplementary Concept]
- CP 101581 [MeSH Supplementary Concept]
- CP 283097 [MeSH Supplementary Concept]
- CP 98113 [MeSH Supplementary Concept]
- ES 242-5 [MeSH Supplementary Concept]
- GW 468816 [MeSH Supplementary Concept]
- Grin3a protein, rat [MeSH Supplementary Concept]
- ID 17263 [MeSH Supplementary Concept]
- ID 17332 [MeSH Supplementary Concept]
- IEM 1754 [MeSH Supplementary Concept]
- IEM 1857 [MeSH Supplementary Concept]
- IEM 1913 [MeSH Supplementary Concept]
- LU 73068 [MeSH Supplementary Concept]
- LY 246492 [MeSH Supplementary Concept]
- N,N'-(6H,12H-5,11-methanodibenzo(b,f)(1,5)diazocine-2,8-diyldi-2,1-ethanediyl)-bis(N-(3-(4-dimethylaminopyridinium)propyl)phenethylamine)dichloride [MeSH Supplementary Concept]
- N,N-(diphenyl)-4-ureido-5,7-dichloro-2-carboxyquinoline [MeSH Supplementary Concept]
- N-(2-(3,5-dimethyl-1-adamantyl)ethyl)acetamidine [MeSH Supplementary Concept]
- N-(2-(4-hydroxyphenyl)ethyl)-5-phenylpentylamine [MeSH Supplementary Concept]
- N-(2-adamantyl)hexamethylenimine [MeSH Supplementary Concept]
- N-(2-methoxy)benzyl 4-trifluomethoxyphenylamidine [MeSH Supplementary Concept]
- N-(2-methoxybenzyl)-3-phenylacrylamidine [MeSH Supplementary Concept]
- N-(3-(3-(4-methylbenzyl)-1,2,4-oxadiazol-5-yl)cyclopentyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine [MeSH Supplementary Concept]
- N-(3-phenethoxybenzyl)-4-hydroxybenzamide [MeSH Supplementary Concept]
- N-(4-phenylbutyl)-4-hydroxycinnamide [MeSH Supplementary Concept]
- N-(cyclohexylmethyl)-2-((5-((phenylmethyl)amino)-1,3,4-thiadiazol-2-yl)thio)acetamide [MeSH Supplementary Concept]
- N-benzylated triamine [MeSH Supplementary Concept]
- N-ethyl-1,4,9,9alpha-4alphaH-fluoren-4alpha-amine [MeSH Supplementary Concept]
- NOC 12 [MeSH Supplementary Concept]
- NPS 1392 [MeSH Supplementary Concept]
- NPS 1506 [MeSH Supplementary Concept]
- PD 158473 [MeSH Supplementary Concept]
- PD 174494 [MeSH Supplementary Concept]
- RPR 104632 [MeSH Supplementary Concept]
- RPR 118723 [MeSH Supplementary Concept]
- SM 18400 [MeSH Supplementary Concept]
- SM 31900 [MeSH Supplementary Concept]
- alpha-phenyl-2-pyridineethanamine dihydrochloride [MeSH Supplementary Concept]
- anti-NMDA receptor autoantibody [MeSH Supplementary Concept]
- bis(propyl)cognitin [MeSH Supplementary Concept]
- conRl-B peptide, conus rolani [MeSH Supplementary Concept]
- conantokin R [MeSH Supplementary Concept]
- conantokin-L [MeSH Supplementary Concept]
- dysiherbaine [MeSH Supplementary Concept]
- glycyldodecylamide [MeSH Supplementary Concept]
- ifenprodil [MeSH Supplementary Concept]
- ro 25-6981 [MeSH Supplementary Concept]
- win 63480 [MeSH Supplementary Concept]
Record concept(s)
- receptors, N-Methyl-D-Aspartate [MeSH concept]
Related MeSH Supplementary Concept(s)
- GRIN1 protein, human [MeSH Supplementary Concept]
- GRIN2C protein, human [MeSH Supplementary Concept]
- GRIN2D protein, human [MeSH Supplementary Concept]
- GRIN3A protein, human [MeSH Supplementary Concept]
- GluN3A protein, mouse [MeSH Supplementary Concept]
- Gprin1 protein, mouse [MeSH Supplementary Concept]
- Grin2d protein, mouse [MeSH Supplementary Concept]
- N-methyl D-aspartate receptor subtype 2A [MeSH Supplementary Concept]
- N-methyl D-aspartate receptor subtype 2D, rat [MeSH Supplementary Concept]
- NETO1 protein, human [MeSH Supplementary Concept]
- NMDA receptor A1 [MeSH Supplementary Concept]
- NMR-1 protein, C elegans [MeSH Supplementary Concept]
- NMR-2 protein, C elegans [MeSH Supplementary Concept]
- NR1 NMDA receptor [MeSH Supplementary Concept]
- NR1A NMDA receptor, rat [MeSH Supplementary Concept]
- NR1A protein, human [MeSH Supplementary Concept]
- NR2A NMDA receptor [MeSH Supplementary Concept]
- NR2B NMDA receptor [MeSH Supplementary Concept]
- NR2B protein (1292-1308) [MeSH Supplementary Concept]
- NR2C NMDA receptor [MeSH Supplementary Concept]
- NR2D NMDA receptor [MeSH Supplementary Concept]
- NR3A NMDA receptor [MeSH Supplementary Concept]
- NR3B NMDA receptor [MeSH Supplementary Concept]
- Neto1 protein, mouse [MeSH Supplementary Concept]
- Nmdar1 protein, Drosophila [MeSH Supplementary Concept]
- grin1b protein, zebrafish [MeSH Supplementary Concept]
See also
- N-Methylaspartate [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- N-Methyl-D-Aspartate Receptor [NCIt concept]
- NMDAR [LOINC component]

Keyword's position in hierarchy(ies) :

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