Interleukin-27 Subunit Beta

Preferred Label : Interleukin-27 Subunit Beta;

NCIt synonyms : IL-27B; EBV-Induced Gene 3 Protein; IL-27 Subunit Beta; Epstein-Barr Virus-Induced Gene 3 Protein; IL27B; EBI3;

NCIt definition : Interleukin-27 subunit beta (229 aa, 25 kDa) is encoded by the human EBI3 gene. This protein plays a role in the regulation of cytokine expression, the modulation of inflammation and the stimulation of innate immunity.;

NCIt note : Interleukin-27 is a heterodimer comprised of interleukin-27 subunit alpha and interleukin-27 subunit beta. Interleukin-27 subunit beta can also form a heterodimer with interleukin-12 subunit alpha; this complex is called interleukin-35. (UniProt);

Details

Origin ID

C117090;

UMLS CUI

C0385988;

OMIM relation
- Epstein-barr virus-induced gene 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- EBI3 protein, human [MeSH Supplementary Concept]
- EBI3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- EBI3 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_is_element_in_pathway
- IL27-Mediated Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Interleukin-27 [NCIt concept]
- Interleukin-35 [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- T-Cell Differentiation [NCIt concept]
- T-Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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