NCIt definition : An immunotherapeutic composed of the Wilms tumor 1 (WT1) and an as of yet undisclosed
adjuvant, with potential antineoplastic activity. Upon administration, the immune
system may be stimulated to exert a cytotoxic T-lymphocyte (CTL) response against
WT1-expressing tumor cells. The adjuvant stimulates the immune system's response to
WT1. WT1, a tumor-associated antigen (TAA) and transcription factor, is overexpressed
in a variety of tumor cell types.;