iNOS Dimerization Inhibitor FK-330

Preferred Label : iNOS Dimerization Inhibitor FK-330;

NCIt related terms : FK-330; iNOS Dimerization Inhibitor ASP9853;

NCIt definition : An orally bioavailable small molecule inhibitor of inducible nitric oxide synthase (iNOS) with potential antineoplastic activity. Upon administration, iNOS Dimerization Inhibitor FK-330 inhibits iNOS dimerization, which results in decreased nitric oxide (NO) production. iNOS expression is upregulated in certain cancers and may invoke a chronic inflammatory state in tumor cells that promotes metastatic growth.;

UNII : K47C68D94B;

CAS number : 442198-67-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 442198-67-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : FK-330; FR-260330;

Details

Origin ID

C116728;

UMLS CUI

C5446288;

Currated CISMeF NLP mapping
- ASP9853 [MeSH Supplementary Concept]
- ASP9853 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ASP9853 [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Nitric Oxide Synthase, Inducible [NCIt concept]

Keyword's position in hierarchy(ies) :

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