Alpha-Hydroxyglutarate

Preferred Label : Alpha-Hydroxyglutarate;

NCIt synonyms : Alpha-Hydroxyglutaric Acid; 2-Hydroxyglutaric Acid; 2-HG; 2-Hydroxy-Pentanedioic Acid; 2-Hydroxypentanedioic Acid; Pentanedioic Acid, 2-Hydroxy-; 2-Hydroxyglutarate; 2HG;

NCIt definition : The base form of alpha-hydroxyglutaric acid, which is an intermediate in the synthesis of alpha-ketoglutaric acid. Alpha-hydroxyglutarate accumulates in the blood of patients with 2-hydroxyglutaric aciduria; an organic acid metabolism disorder, which is caused by the genetic mutation of one of the enzymes responsible for the conversion of 2-hydroxyglutaric acid to alpha-ketoglutaric acid.;

CAS number : 2889-31-8;

Details

Origin ID

C116390;

UMLS CUI

C0051380;

Automatic exact mappings (from CISMeF team)
- 2-hydroxyglutaric acid [MeSH concept]
Currated CISMeF NLP mapping
- 2-Hydroxyglutarate [LOINC component]
- 2-hydroxyglutarate (substance) [SNOMED CT concept]
- alpha-hydroxyglutarate [MeSH concept]
- alpha-hydroxyglutarate [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- 2-Hydroxyglutarate [LOINC component]
- 2-hydroxyglutarate (substance) [SNOMED CT concept]
- alpha-hydroxyglutarate [MeSH Supplementary Concept]
- alpha-hydroxyglutarate [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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