Fluorine F 18 Piflufolastat

Preferred Label : Fluorine F 18 Piflufolastat;

NCIt synonyms : 2-(3-{1-Carboxy-5-[(6-[(18)F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic Acid; Piflufolastat F-18; Fluorine F 18 DCFPyL; 18F-DCFPYL; 2-(3-(1-Carboxy-5-((6-(18f)fluoro-pyridine-3-carbonyl)-amino)-pentyl)-ureido)-pentanedioic Acid; Piflufolastat F18; Piflufolastat F 18;

NCIt definition : A urea-based radiotracer composed of the prostate specific membrane antigen (PSMA) targeting agent DCFPyL and labeled with the positron-emitting isotope, fluorine F 18, that can potentially be used for positron emitting tomography (PET) imaging. Upon administration of fluorine F piflufolastat, piflufolastat binds to PSMA expressed on tumor cells. The fluorine F 18 moiety facilitates PET imaging of PSMA-expressing tumor cells. PSMA, a cell-surface antigen, is abundantly present on the surface of prostate cancer cells and on the neovasculature of most solid tumors.;

UNII : 3934EF02T7;

CAS number : 1207181-29-0;

Drug name : Pylarify;

Origin ID

C116352;

UMLS CUI

C3492634;

Automatic exact mappings (from CISMeF team)
- 18F-JK-PSMA-7 [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- (18F)DCFPyL [MeSH concept]
- Piflufolastat (18F) [SMS substance]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid [MeSH Supplementary Concept]
- 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid [MeSH concept]
- piflufolastat (18F) [ATC Code]
Validated automatic mappings to BTNT
- piflufolastat (18F) [ATC Code]
Validated automatic mappings to NTBT
- 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid [MeSH Supplementary Concept]
- 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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