PLA2R1 wt Allele

Preferred Label : PLA2R1 wt Allele;

NCIt synonyms : PLA2-R; PLA2IR; CLEC13C; PLA2G1R; Phospholipase A2 Receptor 1 Gene; PLA2R; Phospholipase A2 Receptor 1, 180kDa wt Allele;

NCIt definition : Human PLA2R1 wild-type allele is located within 2q23-q24 and is approximately 131 kb in length. This allele, which encodes secretory phospholipase A2 receptor protein, is involved in phospholipase activity and endocytosis.;

NCIt note : There is a report of a chromosomal aberration involving the PLA2R1 gene and the RBMS1 gene, which is associated with breast cancer. (COSMIC);

GenBank Accession Number : U17033;

Details

Origin ID

C114546;

UMLS CUI

C3889278;

Automatic exact mappings (from CISMeF team)
- Phospholipase a2 receptor 1 [OMIM gene]
- group II phospholipases A2 [MeSH Descriptor]
- phospholipases A2, secretory [MeSH Descriptor]
- phospholipases a2 [MeSH Descriptor]
- phospholipases a2, calcium-independent [MeSH Descriptor]
OMIM relation
- Phospholipase a2 receptor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2q23-q24 [NCIt concept]
gene_is_element_in_pathway
- Phagocytosis Pathway [NCIt concept]
gene_plays_role_in_process
- Induction of Cell Senescence [NCIt concept]
- Ligand Binding [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Receptor Mediated Endocytosis [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients