phospholipases A2, secretory

Preferred Label : phospholipases A2, secretory;

MeSH definition : A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes.;

MeSH synonym : secretory phospholipase a2; spla2 phospholipases; spla2s; secreted phospholipases a2; spla(2); phospholipases, spla2; phospholipases a2, secreted; phospholipase a2, secretory; Secretory Phospholipases A2; Secreted Phospholipase A2; A2, Secreted Phospholipase; Phospholipase A2, Secreted; sPLA2;

Registry Number MeSH : EC 3.1.1.4;

MeSH annotation : /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS;

Is substance : O;

UNII : EC 3.1.1.4;

Details

Origin ID

D054497;

UMLS CUI

C2756983;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- (3-aminooxalyl-1-benzyl-2-ethyl-6-methyl-1H-indol- 4-yloxy)-acetic acid methyl ester [MeSH Supplementary Concept]
Record concept(s)
- phospholipases A2, secretory [MeSH concept]
Related MeSH Supplementary Concept(s)
- Bbil-TX protein, bothriopsis bilineata [MeSH Supplementary Concept]
- BrTx-I protein, bothrops roedingeri [MeSH Supplementary Concept]
- bleu TX-III protein, bothrops leucurus [MeSH Supplementary Concept]
- conodipine M [MeSH Supplementary Concept]
- promutoxin, protobothrops mucrosquamatus [MeSH Supplementary Concept]
- secreted phospholipase A2 group XII protein, xenopus [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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