Carboxyhemoglobin

Preferred Label : Carboxyhemoglobin;

NCIt synonyms : COHb;

NCIt definition : Hemoglobin where the heme group has formed a stable complex with carbon monoxide (CO). This complex is produced after CO has been inhaled or as a byproduct of hemoglobin, protoporphyrin or dichloromethane catabolism. The heme-CO complex is approximately 200 times more stable than heme-oxygen complexes. Thus, high levels of carboxyhemoglobin in the circulation can lead to tissue hypoxia and death.;

NCIt note : Tobacco smokers have a higher physiologic percentage of COHb than non-smokers.;

Details

Origin ID

C114300;

UMLS CUI

C0007061;

Automatic exact mappings (from CISMeF team)
- Carboxyhaemoglobin [MedDRA Preferred Term]
- Carboxyhemoglobin [MedDRA LLT]
- carboxyhemoglobin A [MeSH concept]
- carboxyhemoglobin, sickle [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Carbonyl hemoglobin [LOINC component]
- Carboxyhemoglobin [LOINC component]
- Carboxyhemoglobin (substance) [SNOMED CT concept]
- carboxyhemoglobin [MeSH Descriptor]
- carboxyhemoglobin [SNOMED Notion]
- carboxyhemoglobin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Carbonyl hemoglobin [LOINC component]
- Carboxyhemoglobin [LOINC component]
- Carboxyhemoglobin (substance) [SNOMED CT concept]
- carboxyhemoglobin [SNOMED Notion]
- carboxyhemoglobin [MeSH Descriptor]
- carboxyhemoglobin [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Globin Gene [NCIt concept]
gene_product_expressed_in_tissue
- Erythrocyte [NCIt concept]
gene_product_plays_role_in_biological_process
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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