Preferred Label : Gallium Ga 68-labeled MLN6907;
NCIt synonyms : [68Ga]MLN6907;
NCIt definition : A radioconjugate containing a monoclonal antibody directed against guanylyl cyclase
C (GCC) labeled with the radioisotope gallium Ga 68, with positron emission tomography
(PET) imaging activity. The monoclonal antibody moiety of MLN6907 selectively binds
to GCC, a transmembrane receptor normally found on intestinal cells and dopaminergic
neurons in the brain, that is also overexpressed on the surface of a variety of cancer
cells. Upon internalization of the agent and PET, tumors expressing GCC can be visualized.;
NCI Metathesaurus CUI : CL471786;
Origin ID : C113805;
UMLS CUI : C3827039;
Semantic type(s)
- concept_is_in_subset
- has_target
