Preferred Label : Folate Binding Protein J65 Peptide Vaccine;
NCIt synonyms : J65 Peptide Vaccine; FBP J65 Peptide Vaccine;
NCIt definition : A cancer vaccine comprised of human leukocyte antigen (HLA)-A2-restricted folate binding
protein (FBP) epitope J65 (9 amino acids; EIWTFSTKV), with potential immunostimulatory
and antineoplastic activities. Upon intradermal injection, FBP J65 peptide vaccine
may induce a specific cytotoxic T-lymphocyte (CTL) response against J65 FBP-expressing
tumor cell types. FBP is a membrane-bound, tumor-associated antigen overexpressed
in various tumor types, including breast, ovarian and endometrial cancers. J65 is
a strongly immunogenic peptide.;
NCI Metathesaurus CUI : CL458373;
Origin ID : C113660;
UMLS CUI : C3830091;
Semantic type(s)
- concept_is_in_subset
- has_target
