" /> Exemestane - CISMeF





Preferred Label : Exemestane;

NCIt synonyms : 6-Methyleneandrosta-1,4-diene-3,17-dione;

NCIt related terms : Aromasin;

NCIt definition : An irreversible steroidal aromatase inhibitor, with antiestrogen and antineoplastic activities. Upon oral administration, exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the peripheral aromatization of androgens, including androstenedione and testosterone, to estrogens. This lowers estrogen levels in the blood circulation.;

Alternative definition : NCI-GLOSS: A drug used to treat advanced breast cancer and to prevent recurrent breast cancer in postmenopausal women who have already been treated with tamoxifen. It is also being studied in the treatment of other types of cancer. Aromasin causes a decrease in the amount of estrogen made by the body. It is a type of aromatase inhibitor.;

UNII : NY22HMQ4BX;

InChIKey : BFYIZQONLCFLEV-DAELLWKTSA-N;

CAS number : 107868-30-4;

Drug name : Aromasin;

Molecule name : FCE-24304;

Chemical formula : C20H24O2;

NSC code : 713563;

ChEBI ID : CHEBI:4953;

Codes from synonyms : CDR0000045445; NSC0713563; CDR0000508683; 20117; 203;

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06/05/2025


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