Histone H3 Trimethyl Lys4

Preferred Label : Histone H3 Trimethyl Lys4;

NCIt synonyms : H3K4me3 Antigen; Histone H3 Trimethyl Lysine 4; Histone H3 Trimethyl Lysine 5; Histone H3 Trimethyl Lys5;

NCIt related terms : H3K4me3;

NCIt definition : A post-translationally modified form of histone H3 where the lysine residue at position 4 is trimethylated. This modification may be a marker for areas of active gene expression.;

NCIt note : Even though the literature refers to lysine 4 methylation/other modification or amino acid variation/mutation, RefSeq indicates that the lysine is located at amino acid position 5 in histone H3. (see also https://link.springer.com/article/10.1007/s00401-018-1867-2);

Details

Origin ID

C107153;

UMLS CUI

C3829683;

Automatic exact mappings (from CISMeF team)
- histone H3 trimethyl Lys4 [MeSH concept]
Currated CISMeF NLP mapping
- histone H3 trimethyl Lys4 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- histone H3 trimethyl Lys4 [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
related_to_genetic_biomarker
- Histone H3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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