Histone H3 Dimethyl Lys28

Preferred Label : Histone H3 Dimethyl Lys28;

NCIt synonyms : H3K27me2; H3K27me2 Antigen; Histone H3 Dimethyl Lys27; H3K28me2; Histone H3 Dimethyl Lysine 28;

NCIt definition : A post-translationally modified form of histone H3 where the lysine residue at position 28 is dimethylated. This modification may be a marker for transcriptional repression.;

NCIt note : Even though the literature refers to lysine 27 methylation or amino acid variation/mutation, RefSeq indicates that the lysine is located at amino acid position 28 in histone H3. (see https://link.springer.com/article/10.1007/s00401-018-1867-2);

Details

Origin ID

C107151;

UMLS CUI

C3829687;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
related_to_genetic_biomarker
- Histone H3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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