" /> Telisotuzumab - CISMeF





Preferred Label : Telisotuzumab;

NCIt synonyms : Anti-c-Met Monoclonal Antibody ABT-700;

NCIt definition : An immunoglobulin G1 (IgG1) humanized monoclonal antibody directed against human hepatocyte growth factor receptor (HGFR or c-Met), with potential antineoplastic activity. Telisotuzumab binds to c-Met, thereby preventing both c-Met binding to its ligand, HGF and the subsequent activation of the HGF/c-Met signaling pathway. This may cause cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis.;

UNII : R15ZW356HN;

CAS number : 1781223-80-0;

Molecule name : ABT-700;

NCI Metathesaurus CUI : CL433934;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
11/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.