MNX1/ETV6 Fusion Gene

Preferred Label : MNX1/ETV6 Fusion Gene;

NCIt synonyms : MNX1-ETV6 Fusion Gene; HLXB9-ETV6 Fusion Gene; HLXB9/ETV6 Fusion Gene; MNX1::ETV6 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(7;12)(q36;p13) which fuses the first exon of the MNX1 gene with exon 3 of the ETV6 gene. This aberration is associated with infant acute myeloid leukemia.;

NCIt note : The presence of this fusion is associated with poor prognosis.;

Détails

Origin ID

C105817;

UMLS CUI

C3828997;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- MNX1/ETV6 Fusion Protein [NCIt concept]
gene_has_abnormality
- ETS Family Gene Rearrangement [NCIt concept]
gene_involved_in_molecular_abnormality
- t(7;12)(q36;p13) [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Acute Myeloid Leukemia with t(7;12)(q36;p13); HLXB9-ETV6 [NCIt concept]
gene_mapped_to_disease
- Acute Myeloid Leukemia with t(7;12)(q36;p13); HLXB9-ETV6 [NCIt concept]
related_to_genetic_biomarker
- ETV6 Gene [NCIt concept]
- MNX1 Gene [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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