NCIt synonyms : CC; Partially Double-Stranded Circles of Telomeric C-Strand DNA; Extrachromosomal Telomeric C-Rich DNA Circles; C-Circles;
NCIt definition : A stretch of telomeric DNA where the normally guanine-rich (TTAGGG)n overhanging sequence
has gaps while the cytosine-rich (AATCCC)n opposite strand remains intact. The resulting
partially single-stranded telomere can adopt a circular confirmation.;
NCIt note : C-circles may be markers for alternative lengthening of telomeres.;