AKR1C1 wt Allele

Preferred Label : AKR1C1 wt Allele;

NCIt synonyms : H-37; HBAB; MBAB; DDH1; DD1/DD2; DDH; HAKRC; Aldo-Keto Reductase Family 1, Member C1 wt Allele; DD1; C9;

NCIt definition : Human AKR1C1 wild-type allele is located within 10p15-p14 and is approximately 91 kb in length. This allele, which encodes aldo-keto reductase family 1 member C1 protein, plays a role in the conversion of progesterone to its inactive form, 20-alpha-dihydroxyprogesterone, and may have a role in the transport of bile.;

GenBank Accession Number : NM_001353;

Details

Origin ID

C105418;

UMLS CUI

C3540507;

OMIM relation
- Aldo-keto reductase family 1, member 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10p15-p14 [NCIt concept]
gene_is_element_in_pathway
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_plays_role_in_process
- Cholesterol Homeostasis [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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