Secreted Frizzled-Related Protein 2

Preferred Label : Secreted Frizzled-Related Protein 2;

NCIt synonyms : Secreted Apoptosis Related Protein; Secreted Apoptosis-Related Protein 1; sFRP-2; FRP-2; SARP-1;

NCIt definition : Secreted frizzled-related protein 2 (295 aa, 33 kDa) is encoded by the human SFRP2 gene. This protein is involved in regulating cell growth and differentiation as a modulator of Wnt signaling.;

Details

Origin ID

C105003;

UMLS CUI

C1431104;

Automatic exact mappings (from CISMeF team)
- Secreted frizzled-related protein 2 [OMIM gene]
- integrin alpha3 [MeSH Descriptor]
OMIM relation
- Secreted frizzled-related protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SFRP2 protein, human [MeSH Supplementary Concept]
- SFRP2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- SFRP2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Frizzled Domain [NCIt concept]
gene_product_is_element_in_pathway
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Eye Development [NCIt concept]
- Myogenesis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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