CBFA2T2 wt Allele

Preferred Label : CBFA2T2 wt Allele;

NCIt synonyms : EHT; Core-Binding Factor, Runt Domain, Alpha Subunit 2; Translocated to, 2 wt Allele; ZMYND3; MTGR1;

NCIt definition : Human CBFA2T2 wild-type allele is located in the vicinity of 20q11 and is approximately 160 kb in length. This allele, which encodes protein CBFA2T2, may play a role in tumor suppression. This gene is frequently fused to RUNX1 by the t(8;21)(q22;q22) translocation in acute myeloid leukemia.;

GenBank Accession Number : NM_001032999;

Details

Origin ID

C104930;

UMLS CUI

C3540573;

Automatic exact mappings (from CISMeF team)
- Core-binding factor, runt domain, alpha subunit 2, translocated to, 2 [OMIM gene]
- Hypertension, essential [OMIM Phenotype]
OMIM relation
- Core-binding factor, runt domain, alpha subunit 2, translocated to, 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Tumor Suppression [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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