Major Vault Protein

Preferred Label : Major Vault Protein;

NCIt synonyms : Lung Resistance-Related Protein; MVP;

NCIt definition : Major vault protein (893 aa, 100 kDa) is encoded by the human MVP gene. This protein plays a role in both the structure and function of vault ribonucleoprotein complexes.;

NCIt note : The vault ribonucleoprotein particle is a huge cage structure (400 A x 670 A) of 12.9 MDa. It consists of a dimer of half-vaults, each half-vault is comprised of 39 identical major vault protein (MVP) chains, PARP4 and one or more vault RNAs (vRNAs). (UniProt);

Details

Origin ID

C104704;

UMLS CUI

C1097902;

Automatic exact mappings (from CISMeF team)
- Major vault protein [OMIM gene]
- Mitral valve prolapse 1 [OMIM Phenotype]
- major vault protein [MeSH concept]
- major vault protein [MeSH Supplementary Concept]
- major vault protein [HGNC gene]
- mitral valve prolapse [MedlinePlus Topic]
OMIM relation
- Major vault protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MVP protein, human [MeSH concept]
- major vault protein [MeSH Supplementary Concept]
- major vault protein [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- MVP Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_is_physical_part_of
- Ribonucleoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Intracellular Transport [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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