Hepcidin - CISMeF

Preferred Label : Hepcidin;

NCIt synonyms : PLTR; HAMP; LEAP-1; Liver-Expressed Antimicrobial Peptide 1; Putative Liver Tumor Regressor;

NCIt definition : Hepcidin (84 aa, 9 kDa) is encoded by the human HAMP gene. This protein is involved in antimicrobial activity and iron absorption and storage.;

NCIt note : The C-terminus of hepcidin can be cleaved releasing either hepcidin-20 or hepcidin-25. (UniProt);

Details

Origin ID

C104274;

UMLS CUI

C3711683;

Currated CISMeF NLP mapping
- Hepcidin [LOINC component]
- Hepcidin (substance) [SNOMED CT concept]
- hepcidins [MeSH Descriptor]
OMIM relation
- Hepcidin antimicrobial peptide [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- HAMP protein, human [MeSH concept]
- HAMP protein, human [MeSH Supplementary Concept]
- Hepcidin (substance) [SNOMED CT concept]
- hepcidins [MeSH concept]
- hepcidins [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HAMP Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_plays_role_in_biological_process
- Antibacterial Response [NCIt concept]
- Immune System Process [NCIt concept]
is_target
- Anti-hepcidin Monoclonal Antibody LY2787106 [NCIt concept]

Keyword's position in hierarchy(ies) :

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