S-Adenosylhomocysteine

Preferred Label : S-Adenosylhomocysteine;

NCIt synonyms : AdoHCy; S-Adenosyl-L-homocysteine; (S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosine; SAH;

NCIt definition : An amino acid derivative and an intermediate in the synthesis of cysteine and adenosine. S-adenosylhomocysteine (SAH) is formed upon S-adenosylmethionine (SAM)-dependent methylation (homocysteine methionine cycle) of biological molecules, such as DNA, RNA, and proteins. It is then hydrolyzed by S-adenosylhomocysteine hydrolase to form adenosine and homocysteine. As SAH modulates methylation dependent reactions, SAH levels and the ratio of SAH:SAM may be used to assess methylation status of macrocolecules.;

UNII : 8K31Q2S66S;

CAS number : 979-92-0;

Details

Origin ID

C103149;

UMLS CUI

C0036001;

Currated CISMeF NLP mapping
- S-Adenosylhomocysteine [MeSH Descriptor]
- S-Adenosylhomocysteine [MeSH concept]
- S-adenosylhomocysteine [LOINC component]
- s-adenosylhomocysteine [Substance BNPC]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- S-Adenosyl homocysteine (substance) [SNOMED CT concept]
- S-Adenosylhomocysteine [MeSH concept]
- S-Adenosylhomocysteine [MeSH Descriptor]
- S-adenosylhomocysteine [LOINC component]
- s-adenosylhomocysteine [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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