NCIt definition : A peptide vaccine containing the amino acids 267 through 274 of the human immunodeficiency
virus type 1 (HIV-1) gag core protein (gag:267-274), with potential immunostimulating
activity. Upon vaccination, the immune system may exert a potent cytotoxic T-lymphocyte
(CTL) response against the xenoantigen gag:267-274 and produces pro-inflammatory cytokines.
The concomitant administration of a cancer peptide vaccine may benefit from an already
activated immune system and may augment an immune response against the administered
tumor associated antigen(s). Gag:267-274 peptide is highly immunogenic and may potentially
be used as a cancer immunoadjuvant.;