LDB1 wt Allele

Preferred Label : LDB1 wt Allele;

NCIt synonyms : NLI; LIM Domain Binding 1 wt Allele; CLIM2;

NCIt definition : Human LDB1 wild-type allele is located within 10q24-q25 and is approximately 13 kb in length. This allele, which encodes LIM domain-binding protein 1, plays a role in the regulation of gene transcription.;

NCIt note : Mutation of the LDB1 gene may be associated with medulloblastoma. (Nature. 2012; 488:106-110.);

GenBank Accession Number : AF068652;

Details

Origin ID

C102886;

UMLS CUI

C3538767;

OMIM relation
- Lim domain-binding 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10q24-q25 [NCIt concept]
gene_is_element_in_pathway
- Pitx2 Transcription Regulation Pathway [NCIt concept]
gene_plays_role_in_process
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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