Anti-TGF-beta RII Monoclonal Antibody IMC-TR1

Preferred Label : Anti-TGF-beta RII Monoclonal Antibody IMC-TR1;

NCIt definition : A monoclonal antibody directed against transforming growth factor-beta receptor type II (TGF-beta RII) with potential antineoplastic activity. Anti-TGF-beta RII monoclonal antibody IMC-TR1 specifically targets and binds to TGF-beta R11, thereby preventing the activation of TGF-beta RII-mediated signaling pathways. TGF-beta RII is mutated in a number of cancer cell types and is involved in cancer cell proliferation and tumor progression.;

Molecule name : IMC-TR1; LY3022859;

NCI Metathesaurus CUI : CL437134;

Details

Origin ID

C102853;

UMLS CUI

C3640968;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- TGF-Beta Receptor Type-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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