PADI4 wt Allele

Preferred Label : PADI4 wt Allele;

NCIt synonyms : PDI5; PAD; PDI4; PAD4; PADI5; Peptidyl Arginine Deiminase, Type IV wt Allele; Peptidyl Arginine Deiminase, Type V Gene;

NCIt definition : Human PADI4 wild-type allele is located in the vicinity of 1p36.13 and is approximately 56 kb in length. This allele, which encodes protein-arginine deiminase type-4 protein, plays a role in the post-translational protein modification. Mutation of the gene is associated with susceptibility to rheumatoid arthritis.;

NCIt note : Increased expression of the PADI4 gene has been observed in many types of cancer. (J Biol Chem. 2012; 10.1074/jbc.M112.375725.);

GenBank Accession Number : AB017919;

Details

Origin ID

C102549;

UMLS CUI

C3540603;

Automatic exact mappings (from CISMeF team)
- Chronic arterial occlusive disease [Bloc CIM-11]
- Pad (morphologic abnormality) [SNOMED CT concept]
- Pad (unit of presentation) [SNOMED CT concept]
- Pad - unit of product usage (qualifier value) [SNOMED CT concept]
- Padding (qualifier value) [SNOMED CT concept]
- Patent arterial duct [ORDO Disease]
- Peptidylarginine deiminase, type iv [OMIM gene]
- pad [UBERON concept]
- pad, nos [SNOMED Notion]
- peripheral arterial disease [MedlinePlus Topic]
- pulsed amperometric detector [OBI concept]
OMIM relation
- Peptidylarginine deiminase, type iv [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]
- Hydrolysis [NCIt concept]
- Post-Translational Modification [NCIt concept]

Keyword's position in hierarchy(ies) :

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