Preferred Label : MLXIPL wt Allele;
NCIt synonyms : BHLHD14; MONDOB; WS-bHLH; CHREBP; Williams Beuren Syndrome Chromosome Region 14 Gene; WBSCR14; MIO; MLX Interacting Protein-Like wt Allele;
NCIt definition : Human MLXIPL wild-type allele is located in the vicinity of 7q11.23 and is approximately
31 kb in length. This allele, which encodes carbohydrate-responsive element-binding
protein, is involved in the regulation of transcription. Deletion of the gene is associated
with Williams-Beuren syndrome.;
NCIt note : The human MLXIPL gene is expressed as at least 4 isoforms of the carbohydrate-responsive
element-binding protein. The expression of the beta isoform may be associated with
insulin sensitivity. (UniProt and Nature. 2012; 484:333-338.);
GenBank Accession Number : AK055029;
Origin ID : C102475;
UMLS CUI : C3538729;
OMIM relation
Semantic type(s)
allele_in_chromosomal_location
gene_found_in_organism
gene_is_element_in_pathway
gene_plays_role_in_process
https://www.has-sante.fr/jcms/p_3519069/fr/sensura-mio
2024
France
health technology assessment
Drug Delivery System Category
Supper
stoma site, nos
Drug Delivery System
Malignant Germ Cell International Collaborative Risk Classification, Standard
MLXIPL wt Allele
Standard Drug Stability Study
Stomatocyte Count
Stoma
reference standards
Standard
numismatics
support, nos
Device System
Twice
telephone switchboard operator
coins
Mount Device
Protector Device
Standard
equipment and supplies, hospital
Standard Environmental Condition
---
https://www.has-sante.fr/jcms/p_3519072/fr/sensura-mio
2024
France
health technology assessment
Stoma
Device System
coins
stoma site, nos
Stomatocyte Count
numismatics
MLXIPL wt Allele
equipment and supplies, hospital
Protector Device
Drug Delivery System
Supper
convex shape
Drug Delivery System Category
Twice
support, nos
Mount Device
---
https://www.has-sante.fr/jcms/p_3519075/fr/sensura-mio
2024
France
health technology assessment
digestant, nos
Interferon Gamma Treatment was not Administered Prior to Specimen Resection
IDH Family Mutation Analysis Was Not Performed
Norway
IV Anesthesia was not Administered
Additional Surgery for New Metastatic Tumor Event Was Not Performed
No History of Kawasaki Disease
No Known History of Illicit Drug Use
First Degree Family History of Primary Brain Tumor Negative
Minor Criteria for Rheumatic Heart Disease Not Present
Bag
Nitric Oxide Measurement
No History of Neonatal Complication
Bone Marrow Aspirate Immunophenotyping and Cytochemistry Were Not Performed
MGMT Promoter Methylation Testing Was Not Performed
Device System
Pouch Dosing Unit
NRAS Mutation Analysis Was Not Performed
KRAS Mutation Analysis Was Not Performed
ERBB2 Mutation Analysis Was Not Performed
Documentation Absent
First Degree Family History Thyroid Cancer Negative
RET Rearrangement Analysis Was Not Performed
Regional Anesthesia was not Administered
No History of Non-Cardiac Surgery
KIT Mutation Analysis Was Not Performed
Drug Delivery System
IDH Family Wildtype
Another Form of Birth Control was not Used
digestion
No History of Gestational Complication
Pouch
Stoma
Not Lost to Follow-Up
1p/19q Deletion Analysis Was Not Performed
Preoperative IV Opiates were not Administered
EGFR Amplification Analysis Was Not Performed
numismatics
New Tumor Event After Initial Treatment Absent
Adjuvant Post-operative Radiation Therapy Was Not Administered
MET Mutation Analysis Was Not Performed
Evidence of Disease Absent after Completion of Therapy
Lymph Node Dissection Was Not Performed
MLXIPL wt Allele
ATRX Mutation Analysis Was Not Performed
Chief Complaint was Not Witnessed
Intercurrent Illness is Absent at Onset of Chief Complaint
Preoperative IV Sedation was Not Administered
No Known History of Alcohol Use
digestants
Cancer History Absent
Hypertension Absent
PTEN Mutation Analysis Was Not Performed
Routine Cytogenetics Were not Completed
Negation
Chemotherapy Was Not Administered as an Additional Treatment for a New Tumor Event
No History of Congenital Heart Disease
EGFR Gene Amplification Negative
Twice
Any Metastatic Diagnosis Absent
Family History of Stomach Cancer Absent
Additional Surgery for New Tumor Event Absent
ATRX Gene Mutation Negative
Local Anesthesia Agents were not Administered
Additional Immunohistochemistry Was Not Performed
enterostomy
First Degree Family History Cancer Negative
Intervention Not Given for Kawasaki Disease
Neither Case or Control Status
Nitric Oxide
Adjuvant Post-operative Chemotherapy Was Not Administered
digestive tract function, nos
PTEN Gene Mutation Negative
Has No Sibling
Adjuvant Post-operative Immunological Therapy Was Not Administered
History of Medical Treatment Absent
Subsequent Known Primary Melanoma(s) Not Found During the Follow-Up
Digestion
Preoperative IV Antiemetics were not Administered
Chemotherapy Not Received
No History of Other Muscular Dystrophy or Glycogen Storage Disorder
Regular Smokeless Tobacco Use for Six Weeks or More Negative
Unemployed
Preoperative IV Antacids were not Administered
Other Preoperative IV Medications were not Administered
Adjuvant I-131 Therapy Negative
Radiation Was Not Administered as an Additional Treatment for a New Tumor Event
stoma site, nos
ALK Rearrangement Analysis Was Not Performed
Stomatocyte Count
Medication Not Taken
No History of Myopathy
Interferon Gamma Treatment was not Administered 90 Days Prior to Specimen Resection
Neither
PDGFRA Mutation Analysis Was Not Performed
Additional Surgery for New Loco-Regional Tumor Event Was Not Performed
Drug Delivery System Category
Pouch Dosage Form Category
Multiple Known Primary Tumors Absent at Initial Melanoma Diagnosis
Chief Complaint Not Caused by Trauma
Targeted Molecular Therapy Was Not Administered as an Additional Treatment for a New
Tumor Event
NON Mouse
TP53 Mutation Analysis Was Not Performed
Patient was not Postmenopausal with no Prior Oophorectomy
Chemical/Occupational Exposure Absent
coins
SDH Complex Mutation Analysis Was Not Performed
Tumor Reoccurrence Absent After Initial Treatment
Therapeutic Ionizing Radiation to Head History Absent
BRAF Mutation Analysis Was Not Performed
Radiation History Negative
No History of Rheumatic Fever
Immunotherapy Was Not Administered as an Additional Treatment for a New Tumor Event
equipment and supplies, hospital
Physician Diagnosed Diabetes Absent
EGFR Mutation Analysis Was Not Performed
ROS1 Rearrangement Analysis Was Not Performed
History of Colorectal Cancer Negative
Tumor Progression Absent After Initial Treatment
Use of Smokeless Tobacco at Time of Diagnosis Negative
Hormone Therapy Was Not Administered as an Additional Treatment for a New Tumor Event
Patient was Not Previously Evaluated for Current Chief Complaint
Adjuvant Post-operative Targeted Molecular Therapy Was Not Administered
Radiation Therapy Not Received
New Disease is not Multifocal
BRAF Rearrangement Analysis Was Not Performed
Adjuvant Post-operative Pharmaceutical Therapy Was Not Administered
Additional Molecular Studies Were Not Performed
No Response to Intervention for Kawasaki Disease
Paraneoplastic Syndrome is Not Present
Caffeine Not Routinely Consumed
10q23/PTEN Locus Deletion Analysis Was Not Performed
NF1 Mutation Analysis Was Not Performed
Peripheral Blood Immunophenotyping and Cytochemistry Were Not Performed
Fluorescence In Situ Hybridization Was Not Performed
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https://www.has-sante.fr/jcms/p_3519090/fr/sensura-mio
2024
France
health technology assessment
equipment and supplies, hospital
Stomatocyte Count
Murine Urinary System
Urinary System
Exhibit
Stoma
urinary tract, nos
stoma site, nos
urinary tract
Piece Unit
MLXIPL wt Allele
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https://www.has-sante.fr/jcms/p_3519081/fr/sensura-mio
2024
France
health technology assessment
numismatics
Drug Delivery System
coins
enterostomy
Device System
Pouch
Stomatocyte Count
Pouch Dosage Form Category
Drug Delivery System Category
digestive system
digestive tract function, nos
Pouch Dosing Unit
Twice
Bag
digestant, nos
equipment and supplies, hospital
MLXIPL wt Allele
Digestion
Stoma
ostomy collection bag
---
https://www.has-sante.fr/jcms/p_3519084/fr/sensura-mio
2024
France
health technology assessment
MLXIPL wt Allele
stoma site, nos
Stomatocyte Count
Drug Delivery System Category
digestant, nos
Drug Delivery System
equipment and supplies, hospital
Exhibit
Digestion
digestive system
enterostomy
Stoma
Piece Unit
digestive tract function, nos
Device System
---
https://www.has-sante.fr/jcms/p_3519087/fr/sensura-mio
2024
France
health technology assessment
urinary tract, nos
Pouch
Twice
equipment and supplies, hospital
numismatics
Urinary System
MLXIPL wt Allele
Stomatocyte Count
Bag
urinary tract
urinary reservoirs, continent
ostomy collection bag
Pouch Dosing Unit
Stoma
Murine Urinary System
coins
Pouch Dosage Form Category
---
https://www.has-sante.fr/jcms/p_3519078/fr/sensura-mio
2024
France
health technology assessment
Adjuvant Post-operative Pharmaceutical Therapy Was Not Administered
KRAS Mutation Analysis Was Not Performed
Nitric Oxide
Additional Surgery for New Tumor Event Absent
Family History of Stomach Cancer Absent
Preoperative IV Sedation was Not Administered
NON Mouse
No History of Neonatal Complication
EGFR Amplification Analysis Was Not Performed
stoma site, nos
ALK Rearrangement Analysis Was Not Performed
equipment and supplies, hospital
Nitric Oxide Measurement
Adjuvant I-131 Therapy Negative
No History of Myopathy
Drug Delivery System Category
digestion
enterostomy
10q23/PTEN Locus Deletion Analysis Was Not Performed
Additional Molecular Studies Were Not Performed
SDH Complex Mutation Analysis Was Not Performed
No History of Gestational Complication
Medication Not Taken
Fluorescence In Situ Hybridization Was Not Performed
No History of Kawasaki Disease
No Known History of Illicit Drug Use
Another Form of Birth Control was not Used
ATRX Mutation Analysis Was Not Performed
BRAF Mutation Analysis Was Not Performed
Piece Unit
Hypertension Absent
BRAF Rearrangement Analysis Was Not Performed
Immunotherapy Was Not Administered as an Additional Treatment for a New Tumor Event
MLXIPL wt Allele
First Degree Family History Thyroid Cancer Negative
First Degree Family History of Primary Brain Tumor Negative
PTEN Gene Mutation Negative
IDH Family Wildtype
Intervention Not Given for Kawasaki Disease
Adjuvant Post-operative Radiation Therapy Was Not Administered
digestant, nos
IV Anesthesia was not Administered
Cancer History Absent
Patient was not Postmenopausal with no Prior Oophorectomy
Lymph Node Dissection Was Not Performed
No History of Congenital Heart Disease
New Disease is not Multifocal
Norway
Documentation Absent
Additional Immunohistochemistry Was Not Performed
New Tumor Event After Initial Treatment Absent
Evidence of Disease Absent after Completion of Therapy
First Degree Family History Cancer Negative
Additional Surgery for New Metastatic Tumor Event Was Not Performed
No Known History of Alcohol Use
Device System
IDH Family Mutation Analysis Was Not Performed
Chemotherapy Was Not Administered as an Additional Treatment for a New Tumor Event
digestants
Adjuvant Post-operative Immunological Therapy Was Not Administered
Neither Case or Control Status
NF1 Mutation Analysis Was Not Performed
Preoperative IV Antiemetics were not Administered
Additional Surgery for New Loco-Regional Tumor Event Was Not Performed
Other Preoperative IV Medications were not Administered
Bone Marrow Aspirate Immunophenotyping and Cytochemistry Were Not Performed
MET Mutation Analysis Was Not Performed
Tumor Reoccurrence Absent After Initial Treatment
TP53 Mutation Analysis Was Not Performed
Stoma
Not Lost to Follow-Up
History of Medical Treatment Absent
EGFR Gene Amplification Negative
Radiation Therapy Not Received
Subsequent Known Primary Melanoma(s) Not Found During the Follow-Up
Adjuvant Post-operative Targeted Molecular Therapy Was Not Administered
MGMT Promoter Methylation Testing Was Not Performed
Stomatocyte Count
Therapeutic Ionizing Radiation to Head History Absent
Neither
Hormone Therapy Was Not Administered as an Additional Treatment for a New Tumor Event
ROS1 Rearrangement Analysis Was Not Performed
No History of Other Muscular Dystrophy or Glycogen Storage Disorder
Paraneoplastic Syndrome is Not Present
KIT Mutation Analysis Was Not Performed
Physician Diagnosed Diabetes Absent
1p/19q Deletion Analysis Was Not Performed
digestive tract function, nos
Exhibit
Radiation Was Not Administered as an Additional Treatment for a New Tumor Event
Preoperative IV Antacids were not Administered
RET Rearrangement Analysis Was Not Performed
Tumor Progression Absent After Initial Treatment
ERBB2 Mutation Analysis Was Not Performed
Drug Delivery System
No History of Rheumatic Fever
Minor Criteria for Rheumatic Heart Disease Not Present
ATRX Gene Mutation Negative
Chemotherapy Not Received
Adjuvant Post-operative Chemotherapy Was Not Administered
NRAS Mutation Analysis Was Not Performed
History of Colorectal Cancer Negative
Digestion
Any Metastatic Diagnosis Absent
Caffeine Not Routinely Consumed
Radiation History Negative
Intercurrent Illness is Absent at Onset of Chief Complaint
PDGFRA Mutation Analysis Was Not Performed
Chemical/Occupational Exposure Absent
Has No Sibling
Chief Complaint was Not Witnessed
PTEN Mutation Analysis Was Not Performed
Targeted Molecular Therapy Was Not Administered as an Additional Treatment for a New
Tumor Event
Interferon Gamma Treatment was not Administered 90 Days Prior to Specimen Resection
Use of Smokeless Tobacco at Time of Diagnosis Negative
Routine Cytogenetics Were not Completed
Interferon Gamma Treatment was not Administered Prior to Specimen Resection
Unemployed
Negation
Patient was Not Previously Evaluated for Current Chief Complaint
Regional Anesthesia was not Administered
No History of Non-Cardiac Surgery
Regular Smokeless Tobacco Use for Six Weeks or More Negative
Multiple Known Primary Tumors Absent at Initial Melanoma Diagnosis
Preoperative IV Opiates were not Administered
EGFR Mutation Analysis Was Not Performed
Chief Complaint Not Caused by Trauma
No Response to Intervention for Kawasaki Disease
Local Anesthesia Agents were not Administered
Peripheral Blood Immunophenotyping and Cytochemistry Were Not Performed
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