" /> ABRAXAS1 wt Allele - CISMeF





Preferred Label : ABRAXAS1 wt Allele;

NCIt synonyms : FLJ11520; ABRA1; CCDC98; ABRAXAS; Coiled-Coil Domain Containing 98 Gene; Abraxas Gene; UNQ496/PRO1013; FAM175A; FLJ12642; FLJ13614; Family with Sequence Similarity 175, Member A Gene; Family with Sequence Similarity 175 Member A Gene; Abraxas 1, BRCA1 A Complex Subunit wt Allele;

NCIt definition : Human ABRAXAS1 wild-type allele is located in the vicinity of 4q21.23 and is approximately 64 kb in length. This allele, which encodes BRCA1-A complex subunit Abraxas 1 protein, plays a role in the mediation of DNA repair and the progression of the cell cycle.;

NCIt note : Mutation of the FAM175A gene that abrogates the nuclear localization and DNA damage response activities of the gene product is associated with hereditary breast cancer. (Sci Transl Med 2012; 4:122ra23);

GenBank Accession Number : AK023676;

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08/05/2024


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