" /> Olmutinib - CISMeF





Preferred Label : Olmutinib;

NCIt synonyms : 2-Propenamide, N-(3-((2-((4-(4-methyl-1-piperazinyl)phenyl)amino)thieno(3,2-d)pyrimidin-4-yl)oxy)phenyl)-;

NCIt definition : An orally available small molecule, mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild type form.;

UNII : CHL9B67L95;

InChIKey : FDMQDKQUTRLUBU-UHFFFAOYSA-N;

CAS number : 1353550-13-6;

Molecule name : HM61713; BI 1482694;

NCI Metathesaurus CUI : CL435909;

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25/05/2025


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