DDX3X wt Allele

Preferred Label : DDX3X wt Allele;

NCIt synonyms : DDX3; DBX; CAP-Rf; DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked Gene; DDX14; HLP2; DEAD-Box Helicase 3 X-Linked wt Allele; MRX102; MRXSSB; DEAD-Box Helicase 3, X-Linked Gene; DEAD/H Box-3, X-Linked Gene; DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 3 Gene; DEAD (Asp-Glu-Ala-Asp) Box Helicase 3, X-Linked Gene;

NCIt definition : Human DDX3X wild-type allele is located within Xp11.3-p11.23 and is approximately 31 kb in length. This allele, which encodes ATP-dependent RNA helicase DDX3X protein, plays a role in the modulation of RNA structure.;

NCIt note : Mutation of the DDX3X gene may be associated with chronic lymphocytic leukemia. (N Engl J Med 2011; 365:2497-2506.);

GenBank Accession Number : U50553;

Details

Origin ID

C101566;

UMLS CUI

C3538709;

Automatic exact mappings (from CISMeF team)
- DEAD-box helicase 3 X-linked [ORDO Gene]
- Dead-box helicase 3, X-linked [OMIM gene]
- Developing brain homeobox 1 [OMIM gene]
- HLP-2 [MeSH concept]
OMIM relation
- Dead-box helicase 3, X-linked [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- Xp11.3-p11.23 [NCIt concept]
gene_is_element_in_pathway
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- ATP Hydrolysis [NCIt concept]
- Hydrolysis [NCIt concept]
- RNA Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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