P4HA2 wt Allele

Preferred Label : P4HA2 wt Allele;

NCIt synonyms : Prolyl 4-Hydroxylase, Alpha Polypeptide II wt Allele; 4-PH Alpha 2 Gene; Collagen Prolyl 4-Hydroxylase Alpha(II)Gene; C-P4Halpha(II) Gene; UNQ290/PRO330;

NCIt definition : Human P4HA2 wild-type allele is located in the vicinity of 5q31 and is approximately 103 kb in length. This allele, which encodes prolyl 4-hydroxylase subunit alpha-2 protein, plays a role in procollagen processing.;

NCIt note : Expression of the P4HA2 gene (along with the MMP1, COL4A1, and THBS2 genes) in histologically normal surgical margins may be a prognostic marker for oral carcinoma recurrence. (BMC Cancer 2011, 11:437-447.);

GenBank Accession Number : U90441;

Details

Origin ID

C101550;

UMLS CUI

C3542975;

OMIM relation
- Procollagen-proline, 2-oxoglutarate-4-dioxygenase, alpha subunit, isoform 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q31 [NCIt concept]
gene_is_element_in_pathway
- Arginine and Proline Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Post-Translational Modification [NCIt concept]

Keyword's position in hierarchy(ies) :

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