Preferred Label : Folate Binding Protein E39 Peptide Vaccine;
NCIt synonyms : FBP E39 Peptide Vaccine; E39 Peptide Vaccine;
NCIt definition : A cancer vaccine comprised of human leukocyte antigen (HLA) A2 restricted folate binding
protein (FBP) epitope E39 (amino acids 191 to 199), with potential immunostimulatory
and antineoplastic activity. Upon intradermal injection, FBP E39 peptide vaccine may
induce a specific cytotoxic T-lymphocyte (CTL) response against FBP-expressing tumor
cell types. FBP is a membrane-bound, tumor-associated antigen highly overexpressed
in various tumor cell types, such as in breast, ovarian and endometrial cancers; E
39 is a strong immunogenic peptide.;
NCI Metathesaurus CUI : CL435783;
Origin ID : C101530;
UMLS CUI : C3640132;
Semantic type(s)
- concept_is_in_subset
- has_target
