Cation Channel Sperm-Associated Protein Subunit Zeta

Preferred Label : Cation Channel Sperm-Associated Protein Subunit Zeta;

NCIt synonyms : Hypothetical Protein LOC25858; Testis-Expressed Protein 40; CatSperzeta; Testis-Expressed Sequence 40 Protein; Uncharacterized Protein C11orf20; CatSper-Zeta; CATSPERZ;

NCIt definition : Cation channel sperm-associated protein subunit zeta (200 aa, 23 kDa) is encoded by the human CATSPERZ gene. This protein is involved in sperm capacitation.;

NCIt note : Cation channel sperm-associated protein subunit zeta is an auxillary subunit of the CatSper complex. The CatSper complex, a sperm-specific voltage-gated calcium channel, plays a role in modulating intracellular calcium ion concentration and sperm cell hyperactivation. (UniProt and GO);

Details

Origin ID

C101397;

UMLS CUI

C3640104;

OMIM relation
- Cation channel, sperm-associated, auxiliary subunit zeta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- CATSPERZ Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_expressed_in_tissue
- Testis [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Motility [NCIt concept]
- Spermatogenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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