Danvatirsen - CISMeF

Preferred Label : Danvatirsen;

NCIt definition : An antisense oligonucleotide targeting signal transducer and activator of transcription 3 (STAT3) with potential antitumor activity. Danvatirsen binds to STAT3 mRNA, thereby inhibiting translation of the transcript. Suppression of STAT3 expression induces tumor cell apoptosis and decreases tumor cell growth. STAT3, a protein overexpressed in a variety of human cancers, plays a critical role in tumor cell growth and survival.;

UNII : 31N550RD05;

CAS number : 1402357-06-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1402357-06-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : ISIS-STAT3rx;

Molecule name : ISIS 481464; AZD9150;

NCI Metathesaurus CUI : CL435548;

Details

Origin ID

C101368;

UMLS CUI

C4682383;

Currated CISMeF NLP mapping
- danvatirsen [MeSH concept]
- danvatirsen [MeSH Supplementary Concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- danvatirsen [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Signal Transducer and Activator of Transcription 3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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