CDK12 wt Allele

Preferred Label : CDK12 wt Allele;

NCIt synonyms : Cdc2-Related Kinase, Arginine/Serine-Rich Gene; CRKR; KIAA0904; CRK7; CRKRS; Cyclin-Dependent Kinase 12 Gene; CDC2 Related Protein Kinase 7 Gene; hCDK12; Cyclin Dependent Kinase 12 wt Allele;

NCIt definition : Human CDK12 wild-type allele is located in the vicinity of 17q12 and is approximately 73 kb in length. This allele, which encodes cyclin-dependent kinase 12 protein, plays a role in the modulation of protein phosphorylation. Chromosomal deletions within the 17q12 region can lead to out of frame fusions of this gene and the ERBB2 gene and may be associated with gastric cancer.;

GenBank Accession Number : AF227198;

Details

Origin ID

C101096;

UMLS CUI

C3539634;

OMIM relation
- Cyclin-dependent kinase 12 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q12 [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- RNA Splicing [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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