NCIt definition : A fusion protein encoded by the BCR/JAK2 fusion gene. This protein is comprised of
the N-terminal coiled-coil domain of breakpoint cluster region protein fused to the
C-terminal JH1 tyrosine kinase domain of tyrosine-protein kinase JAK2.;
NCIt note : The BCR/JAK2 fusion protein is a constitutively oligomerized and activated tyrosine
kinase.;