BCR/JAK2 Fusion Protein

Preferred Label : BCR/JAK2 Fusion Protein;

NCIt synonyms : Breakpoint Cluster Region Protein/Tyrosine-Protein Kinase JAK2 Fusion Protein; BCR-JAK2 Fusion Protein; BCR::JAK2 Fusion Protein; Breakpoint Cluster Region Protein::Tyrosine-Protein Kinase JAK2 Fusion Protein;

NCIt definition : A fusion protein encoded by the BCR/JAK2 fusion gene. This protein is comprised of the N-terminal coiled-coil domain of breakpoint cluster region protein fused to the C-terminal JH1 tyrosine kinase domain of tyrosine-protein kinase JAK2.;

NCIt note : The BCR/JAK2 fusion protein is a constitutively oligomerized and activated tyrosine kinase.;

Détails

Origin ID

C101049;

UMLS CUI

C3639962;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BCR/JAK2 Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- BCR Gene [NCIt concept]
- JAK2 Gene [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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